Research & Economic Development

Office of the Vice Chancellor

Protocol-Proposal Congruency

The UMKC Office of Research Services is responsible for ensuring that all animal activity proposed in a funding proposal has been approved by the IACUC and is covered in an active, approved IACUC protocol (i.e. protocol to proposal congruency). 

A Congruency Review must be completed for grants proposing animal studies before the award of funds either at JIT notice or Notice of Award for the following funding agencies:

  • National Institutes of Health (NIH)
  • All NIH subdivisions (e.g. NCI, NHLBI, NIAID, NIDDKD, NIAAA, etc.)
  • National Science Foundation (NSF)
  • American Heart Association (AHA)
  • American Cancer Society (ACS)
  • Veterans Affairs (VA)
  • March of Dimes (MOD)

The UMKC IACUC will conduct a congruency review between the proposal and the protocol to ensure the work described in the proposal comports with the protocol.  If there are discrepancies between the proposal and protocol, the IACUC will request a modification to the protocol to achieve congruence.  Note that investigators can submit a protocol modification prior to requesting a congruency review and this is highly recommended in instances where the animal work proposed is not yet covered in an approved protocol. 

Any award involving animal work requires a congruency review and IACUC congruency approval before UMKC Sponsored Programs will release funds associated with that award.  Some sponsors require proof of IACUC congruency approval at the time of submission.  When congruency is established, the UMKC IACUC will provide documentation to the investigator.   

The chart below shows the typical path of a congruency review.  If you have any questions about congruency requirements, please contact us at

 Helpful link to OLAW Webinar on Congruency                                                


Congruency Review Flow Chart